<p>Sometime in the near future, paraplegic prison inmate Matt Mills meets "The Board" of Satoshi-Telefair Industries, who thank him for joining the Program. Under pressure and with a promise to make him walk again, Mills agrees to volunteer. He is injected with a synthetic nanomaterial and suffocated, only to wake up with restored use of his legs, yet alone in a steel cell in the first spoke of an experimental apparatus - The Wheel. A series of assailants inflict a multitude of damage to Mills' body and torment his mind, yet the synthetic nanomaterial not only restores his damaged organs, it re-engineers his strength. The experiment might be designed to kill, but Mills is determined to survive - and get back to his daughter before The Board finds her first.</p>...
在上集幸存下来的人被神秘的先知Shot Bus Gus所救,他似乎拥有控制这些畜生的能力,在先知的带领下,幸存者进入下水道,那可通往城市,路上他们得到了空手道专家Jean-Claude Seagal的帮助,并得知这些畜生源自一个叫"The Hive."的地方,于是他们决定发起反击,永远消灭掉这些畜生。...